Technology is evolving at an unprecedented pace, and the boundaries between artificial intelligence and biological intelligence are becoming increasingly blurred. In a groundbreaking achievement, an Australian startup, Cortical Labs, has unveiled the world’s first commercial computer powered by living human brain cells.
Dubbed the CL1, this biological computing system could revolutionize AI, robotics, and the way we process information. But how does it work? What are its implications? And could it be the next step in merging human cognition with machine intelligence?
A Revolutionary Leap: What is the CL1?

The CL1 is a biological computer that operates using lab-grown human neurons, effectively mimicking the way a human brain functions. It was launched at the Mobile World Congress in Barcelona, where researchers and tech enthusiasts alike marveled at its potential.
Cortical Labs describes the device as a “body in a box”, meaning it is a contained system that supports living brain cells while performing computational tasks. Unlike traditional computers, which rely on silicon-based processors, the CL1 harnesses biological intelligence, enabling it to learn, adapt, and execute commands with minimal energy consumption.
How Does a Computer Run on Human Brain Cells?
The CL1’s core technology is based on lab-grown neurons that are cultivated on a silicon chip. These neurons can send and receive electrical impulses, functioning similarly to the neural networks in a living brain.
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Here’s how the system works:
✔ Biological Integration – The neurons grow on a specially designed chip, allowing them to communicate with the system just like brain cells do in the human body.
✔ The biOS Operating System – Cortical Labs has developed a Biological Intelligence Operating System (biOS) that interacts with the neurons, enabling users to execute commands and perform computing tasks.
✔ Life Support System – Since the neurons are living cells, they require constant care. The system includes pumps, gas regulators, and temperature controls to keep them alive for up to six months.
CL1 vs. Traditional AI: Why Biological Intelligence is Different
The CL1 is not just another AI system—it’s something far more advanced. While conventional AI requires massive amounts of data and computational power to function, biological intelligence offers unique advantages:
🔹 Self-Learning Ability – Unlike traditional AI, which depends on pre-programmed datasets, neurons can learn on their own with minimal input.
🔹 Energy Efficiency – AI models like ChatGPT or image recognition systems consume enormous amounts of electricity. The human brain, by contrast, runs on just 20 watts of power—far less than any silicon-based computer. The CL1 operates on a similar principle, using a fraction of the energy required by traditional AI.
🔹 Adapting in Real-Time – Biological intelligence does not require millions of examples to learn something new. It can adjust on the fly, much like a human learning from experience.

Teaching a Brain Cell Computer to Play Pong
Cortical Labs previously conducted an experiment in which 800,000 human and mouse neurons were integrated into a system and trained to play the video game Pong. The neurons learned to respond to the game’s mechanics, showing signs of adaptation and sentience-like behavior.
A study published in the journal Cell confirmed that these neurons were learning in real-time and interacting with their environment, a phenomenon rarely seen in artificial intelligence.
This raises an important question—are these computers truly conscious?
Ethical Concerns: Are We Creating Living AI?
As with any breakthrough in biotechnology, there are ethical concerns surrounding the use of living neurons in computing. If a system made of human brain cells can learn and react, could it eventually develop consciousness?
Cortical Labs has addressed these concerns, stating that they have put strict guardrails in place to prevent any form of artificial sentience. However, they have provided few details on exactly how they ensure this.
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Critics argue that if biological computing continues to advance, it may eventually reach a point where the neurons are capable of self-awareness—forcing society to confront complex moral dilemmas.
Commercial Availability and Future Applications
The first CL1 computers are expected to be shipped to researchers and developers by June 2024, with each unit priced at approximately $35,000 (£27,000).
While initially targeted at scientists and AI researchers, the long-term goal is to democratize biological computing, making it accessible to a wider audience.
Potential applications include:
✔ Advanced AI Systems – Biological intelligence could outperform current AI models, allowing machines to think more like humans.
✔ Medical Research – Studying how neurons interact in the CL1 could lead to breakthroughs in neurological diseases, brain injuries, and Alzheimer’s research.
✔ Energy-Efficient Computing – The CL1 could lead to the development of low-energy AI systems, reducing global energy consumption.
The Future of AI and Biological Computing
The CL1 is just the beginning. As technology advances, we may see biological computers that can solve problems far beyond the capabilities of traditional AI.

Imagine a world where:
🚀 AI can learn and adapt like a human, without needing massive amounts of training data.
🚀 Computers use a fraction of today’s energy, making AI more sustainable.
🚀 Scientists develop treatments for brain disorders by studying biological computing.
Final Thoughts: A New Era of Intelligence?
The CL1 biological computer is not just a technological advancement—it’s a paradigm shift. Merging biology with computing could redefine the future of artificial intelligence, neuroscience, and even human-machine integration.
Will biological computers surpass traditional AI? Could they one day develop human-like cognition? And how will society navigate the ethical implications of machines powered by living neurons?
As Cortical Labs prepares to ship the world’s first commercial brain-cell-powered computers, one thing is clear—we are entering an era where machines and biology become one.
What do you think about this groundbreaking innovation? Let us know in the comments!